Top 10 Healthcare Software Product Development Companies in The USA 2025

The healthcare industry in the USA is rapidly adopting digital solutions to improve patient care, streamline operations, and ensure data security. As hospitals, clinics, and health startups search for smarter ways to manage patient records and deliver virtual care, the demand for healthcare software development companies in the USA continues to grow. These companies play a vital role in building secure, scalable, and compliant medical platforms that align with the industry’s evolving needs.

From custom healthcare software development to advanced EHR and EMR solutions, top firms help healthcare providers automate workflows, improve diagnostics, and deliver personalized patient experiences. Whether you’re a hospital looking for HIPAA-compliant software development in the USA or a healthtech startup needing a telemedicine platform, the right partner can make all the difference. That’s why many providers turn to top medical software companies in the USA to meet their unique software needs.

In this blog, we’ve highlighted the top 10 healthcare IT companies in the USA for 2025 based on their expertise, innovation, client satisfaction, and industry impact. These companies specialize in a wide range of services—from healthcare mobile app development to SaaS product development—and help transform how healthcare systems operate across the country.

If you’re looking to build a digital health platform, choosing from one of these healthcare software development firms in the USA ensures that you’re working with experts who understand healthcare regulations, patient privacy, and the need for scalable, future-ready solutions.

Software Product in Healthcare – Statistics & Facts

According to Grand View Research, the global healthcare Software as a Service (SaaS) market was valued at USD 25.13 billion in 2024 and is expected to grow at a 20.0% CAGR from 2025 to 2030. This growth comes from more healthcare providers using cloud-based solutions, the rising demand for remote care, and the need for affordable, secure systems. Government support, digital transformation, and new technologies are also helping this market grow. Additionally, the focus on patient engagement, better data security, and simplified healthcare management is boosting the adoption of healthcare SaaS.

Key Selection Criteria for Healthcare Software Product Development Companies in the USA

Choosing the right partner from the top healthcare IT companies in the USA is essential when developing a reliable healthcare software product. In 2025, many healthcare software development companies in the USA stand out by offering industry knowledge, tech expertise, and compliance-ready solutions. Here’s what to look for when picking the best fit for your healthcare project.

Expertise in Solving Healthcare Challenges

Leading healthcare software development firms in the USA understand the unique challenges of the healthcare sector. Whether it’s building Electronic Health Record (EHR) software or developing telemedicine apps, these companies know how to create tools that healthcare professionals actually use. Review their past work in custom EMR software development or healthcare app development to see how they improve patient care and streamline clinical tasks.

Commitment to HIPAA Compliance and Data Security

Top HIPAA-compliant software development companies design systems that keep sensitive data secure. They follow all regulations and implement encryption, secure cloud storage, and strict access controls. Ask how they’ve helped clients meet healthcare compliance requirements. This step protects your business from costly legal issues while ensuring patient trust.

Innovation Through Modern Technology

The best medical software product development companies use the latest tech—like AI, IoT, and cloud platforms—to power their solutions. Whether you need healthcare SaaS product developers or a team for AI-driven remote care apps, your partner should understand the future of healthcare. Their use of innovation ensures your software stays competitive and effective in a fast-changing world.

Real Results and Happy Clients

Don’t just rely on websites or sales pitches. Explore platforms like Clutch or GoodFirms to find reviews of the best healthcare software companies in the USA. Look for proof of results—faster workflows, better patient communication, or increased data accuracy. These success stories show that the company delivers real value.

Scalability and Long-Term Support

Your needs will grow, and your software should keep up. Trusted custom healthcare software development companies in the USA offer flexible solutions that adapt to your changing requirements. They also provide ongoing support and maintenance to ensure smooth performance after launch. Their commitment to post-launch care shows that they stand by their product.

List of Top 10 Healthcare Software Product Development Companies in the USA – 2025

The top healthcare software development companies in the USA are transforming the medical industry in 2025. These US-based healthcare software vendors build innovative and secure solutions like EHR software, telemedicine apps, and HIPAA-compliant platforms that improve patient care and provider efficiency. Each company follows strict healthcare standards and leads in health tech innovation. Here’s your updated list of the top 10 healthcare IT companies in the USA, ready to turn your healthcare vision into reality.

1. Zealous System

Zealous System stands out among the best healthcare software companies in the USA for delivering customized solutions that meet the unique needs of medical providers. Their team builds everything from Electronic Health Record (EHR) software and telehealth applications to AI-powered healthcare tools, helping clinics and hospitals work smarter. As a leading healthcare software development company in the USA, Zealous System focuses on creating HIPAA-compliant software that improves care quality while maintaining data security. Their solutions, including custom EMR software and healthcare SaaS products, streamline clinical workflows and enhance data access across devices.

Zealous also leads the way in custom healthcare software development by building scalable platforms using cloud and IoT technologies. Their experience as a telemedicine app development company and healthcare mobile app developer allows them to offer user-friendly, future-ready software for both small practices and large hospitals. By combining innovation with compliance, Zealous System has earned a reputation as one of the most reliable healthcare IT service providers in the USA. In 2025, they continue to set the bar for modern healthcare software solutions that support patient engagement and operational success.

Key Information:

• Founding Year: 2008
• Employees: 50–249
• Hourly Rate: $50 – $99 / hr
• Clutch Rating: 4.8/5
• Location: Lewis Center, OH

2. Gleaming Systems

Gleaming Systems is a trusted custom software development company in the USA that builds powerful, AI-driven healthcare platforms. Their solutions include advanced patient management systems, health analytics tools, and custom telehealth app development services that help medical professionals deliver smarter care. Each platform complies with HIPAA-compliant software development practices to ensure patient data remains safe and secure.

As one of the most innovative health tech companies USA, Gleaming Systems also specializes in predictive analytics tools that help healthcare providers identify potential health risks early. Their development team builds custom healthcare software that integrates smoothly with existing medical systems and EHRs. Their real-time communication apps improve patient-provider interaction, making them a trusted name among healthcare mobile app developers in the USA.

3. Epic Systems Corporation

Cerner, now part of Oracle Health, continues to lead in custom healthcare software development in the USA. Their Millennium platform offers a comprehensive suite of solutions that connect patient data across hospitals and health systems, improving care coordination. As one of the top medical software companies USA, Cerner leverages Oracle’s powerful cloud infrastructure to ensure high scalability and secure access to health records.

They focus heavily on population health management, interoperability, and real-time analytics. Cerner is also a trusted name in telemedicine app development, offering HIPAA-compliant tools for remote consultations. Their work with major providers like AdventHealth shows their deep commitment to innovation and healthcare software solutions USA.

4. Cerner Corporation (Oracle Health)

Cerner, now part of Oracle Health, continues to lead in custom healthcare software development in the USA. Their Millennium platform offers a comprehensive suite of solutions that connect patient data across hospitals and health systems, improving care coordination. As one of the top medical software companies USA, Cerner leverages Oracle’s powerful cloud infrastructure to ensure high scalability and secure access to health records.

They focus heavily on population health management, interoperability, and real-time analytics. Cerner is also a trusted name in telemedicine app development, offering HIPAA-compliant tools for remote consultations. Their work with major providers like AdventHealth shows their deep commitment to innovation and healthcare software solutions USA.

5. Allscripts (Veradigm)

Now operating under the name Veradigm, Allscripts specializes in developing custom healthcare software for ambulatory care and smaller health facilities. Their EHR platform, Veradigm EHR, helps clinics manage clinical data efficiently while staying compliant with privacy laws. As one of the best healthcare software companies in the USA, they focus on creating systems that are intuitive and easily integrated.

Their FollowMyHealth platform supports telehealth consultations and helps improve patient engagement by giving users easy access to their medical records. Veradigm stands out among healthcare software development firms USA for its open architecture, which makes integration with third-party systems seamless. Their HIPAA-compliant tools are built for flexibility, scalability, and ease of use.

6. Meditech

Meditech is a prominent name among US-based healthcare software vendors, offering cloud-first EHR solutions through its Expanse platform. Their focus is on improving clinical efficiency, documentation, and patient-centered care. Meditech supports healthcare app development services that are tailored to hospitals and community clinics alike.

Their systems are well-regarded for their interoperability, helping providers like Beth Israel integrate their existing data infrastructure with ease. Meditech also supports mobile access, which allows healthcare professionals to update patient information in real-time. With a proven track record in HIPAA-compliant software development USA, Meditech continues to be a reliable provider of scalable healthcare software solutions in 2025.

7. Athenahealth

Athenahealth is widely known for its easy-to-use, cloud-based healthcare software solutions in the USA. Their main offering, athenaOne, brings together EHR, revenue cycle management, and patient engagement in one platform. It’s designed to reduce the administrative burden on medical professionals and boost overall productivity.

They also offer telehealth apps and mobile tools that improve virtual care access for patients. As a trusted telemedicine app developer in the USA, Athenahealth uses data-driven insights and AI features to streamline healthcare delivery. Their platforms are fully HIPAA-compliant, making them a reliable partner for healthcare IT service providers USA in 2025.

8. NextGen Healthcare

NextGen Healthcare caters to the needs of smaller clinics and private practices with its affordable, custom healthcare software development services. Their NextGen Office solution is a cloud-based EHR that includes telehealth, patient messaging, and billing tools—all designed with simplicity in mind.

They are one of the leading healthcare software development companies in the USA that offer flexible, scalable platforms for ambulatory care providers. With advanced analytics dashboards and seamless integration options, they help clinics enhance patient engagement and improve clinical outcomes. Their platforms remain fully compliant with healthcare regulations in 2025.

9. eClinicalWorks

eClinicalWorks is a powerhouse in healthcare app development companies USA, offering comprehensive EHR and telemedicine solutions. Their cloud-based platform, eClinicalWorks V12, provides robust features for clinical documentation, appointment scheduling, and real-time data exchange between providers.

They serve a wide range of healthcare organizations, including community health centers and mid-sized practices. As one of the most reliable custom EMR software companies USA, they prioritize data security, ease of use, and cost-efficiency. Their platforms help improve patient satisfaction by enabling convenient access to care through digital portals and mobile apps.

10. Imaginovation

Imaginovation is a growing name in healthcare software development firms USA, known for their fully customized software products tailored to startups, clinics, and emerging health tech companies. They specialize in HIPAA-compliant mobile apps, telehealth platforms, and real-time remote patient monitoring tools.

Their agile development process allows for quick iteration and personalized features that align with unique clinical workflows. Client testimonials on Clutch highlight their strong communication, technical expertise, and post-launch support. As a rising healthcare SaaS product developer, Imaginovation continues to push the envelope for digital health in 2025.

Conclusion

The future of healthcare relies on smart, secure, and scalable technology. The top healthcare software development companies in the USA featured in our list bring powerful solutions that help hospitals, clinics, and startups stay ahead in 2025. Each software product development company in the USA we’ve included delivers innovative tools that solve real-world medical challenges.

Whether you need custom healthcare software development in the USA, a reliable EHR software company, or experienced telemedicine app developers, these firms have proven their value. Their deep expertise in HIPAA-compliant software development and healthcare mobile app solutions ensures better patient care and smoother operations.

Don’t wait to transform your healthcare services. Explore our top picks, review each firm’s strengths, and connect with the right health tech company or software product development company in the USA for your needs. With the right partner, you can launch cutting-edge solutions—from custom EMR software to advanced healthcare SaaS product development—and redefine the way you deliver care in 2025 and beyond.